human plasma — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16369	O-Desmethyl gefitinib		EGFR
	O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 acti...		EGFR
T1736	Apixaban	BMS-562247-01	Factor Xa
	Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr...		Factor Xa
TP1158	Copper tripeptide	GHK-Cu	Others , Endogenous Metabolite
	Copper tripeptide (GHK-Cu) is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found...		Others , Endogenous Metabolite
T12372	PAT-505		EGFR
	PAT-505 is an orally available, selective and potent inhibitor of autologous epidermal growth factor (IC50 2 nM in Hep3B cells, 9.7 nM in human blood, 62 nM in mouse plasma).		EGFR
T60104	Mycophenolic acid-β-D-glucuronide solution		Others
	Mycophenolic acid glucuronide is the glucuronide metabolite of mycophenolic acid in human plasma.		Others
TP2124L	Somatostatin 1-28 acetate	Somatostatin 1-28 acetate(74315-46-1 Free base)	Somatostatin
	Somatostatin 1-28 acetate circulates in human plasma. Approximately 46% of the total somatostatin-like immunoreactivity in plasma is due to Somatostatin 1-28 acetate.		Somatostatin
T6999	Teneligliptin hydrobromide	Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide)	Others , Proteasome , DPP-4
	Teneligliptin hydrobromide (MP-513 (hydrobromide)) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 ...		Others , Proteasome , DPP-4
T5269	N-Acetylornithine	Acetyl-ornithine,N-Acetyl-L-ornithine	Others , Endogenous Metabolite
	N-Acetylornithine (N-Acetyl-L-ornithine) is a minor component of deproteinized blood plasma of human blood. Human blood plasma contains a variable amount of acetylornithine, averaging 1.1 +/- 0.4 μmol/L. Urine contains a...		Others , Endogenous Metabolite
T5573	Coenzyme Q9	Ubiquinone Q9,Ubiquinone 9,CoQ9	Apoptosis , Endogenous Metabolite
	Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.		Apoptosis , Endogenous Metabolite
TN1305	Ethoxysanguinarine	6-Ethoxydihydrosanguinarine	Apoptosis , AChR
	Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/-...		Apoptosis , AChR
T36926L	Neuropeptide SF (human) aceate		Others
	Neuropeptide SF (human) aceate is a neuropeptide that augmented paraventricular CRH release and increased ACTH and corticosterone levels in the plasma.		Others
TN6752	Dimethyl sulfone		Endogenous Metabolite
	Dimethyl sulfone exists in all living organisms, ranging from bacteria to humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Dimethyl sulfone ...		Endogenous Metabolite
T17232	Vidupiprant	AMG 853	Prostaglandin Receptor
	Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in studies about the treatment of asthma.		Prostaglandin Receptor
TN6710	Methyl acetylsalicylate	ACETYLSALICYLIC ACID METHYL ESTER	Others
	Methyl acetylsalicylate (ACETYLSALICYLIC ACID METHYL ESTER) is a natural product isolated from Pisum sativum. Inhibition of collagen-induced human platelet rich plasma aggregation		Others
T2655	CEP-37440	CEP37440	FAK , ALK
	CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).		FAK , ALK
T4810	Pyrocatechuic acid	3-Hydroxysalicylic acid,O-Pyrocatechuic acid,Catecholcarboxylic acid,NSC 27435,2,3-Dihydroxybenzoic acid	Others , Endogenous Metabolite
	Pyrocatechuic acid (Catecholcarboxylic acid), a normal human benzoic acid metabolite found in plasma, has increased levels after aspirin ingestion.		Others , Endogenous Metabolite
T5219	L-Alloisoleucine	L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine	Others , Endogenous Metabolite
	L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of...		Others , Endogenous Metabolite
TP1116L	Kinetensin acetate(103131-69-7 free base)	Kinetensin (human) acetate	Neurotensin Receptor
	Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.		Neurotensin Receptor
T5295	1-Hydroxyoctadecane	1-Octadecanol,Stearyl alcohol,Octadecanol	Others , Endogenous Metabolite
	1-Hydroxyoctadecane (OctadecanolOctadecanol) is a fatty alcohol present in human and is normally incorporated into plasmalogen lipids. Sjogren-Larsson syndrome is defined by the triad of ichthyosis, mental retardation, a...		Others , Endogenous Metabolite
T5303	Isethionic acid sodium salt	Sodium isethionate	Others , Endogenous Metabolite
	Isethionic acid sodium salt (Sodium isethionate) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. Mammals are able to endogenously synthesize Isethionic acid sodium salt v...		Others , Endogenous Metabolite